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Enzymatic debridement involves the application of topical enzymes, such as collagenase or papain-urea, to break down necrotic tissue and promote autolytic debridement. This method is often used for wounds with minimal exudate and can be beneficial for patients who cannot tolerate or undergo sharp debridement. Enzymatic debridement involves the application of topical enzymes, such as collagenase or papain-urea, to break down necrotic tissue and promote autolytic debridement. This method is beneficial for wounds with minimal exudate and can be used in conjunction with wound debridement techniques to enhance tissue removal and wound healing. Autolytic debridement utilizes the body's natural processes to break down necrotic tissue through the use of occlusive dressings that maintain a moist wound environment.

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